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睿康?硬腦(脊)膜補片

可縫可貼 · 適用于硬腦(脊)膜缺損時的外科修補術(shù)
可縫可貼

睿康?易展開、具有良好的貼附能力。

可縫可貼
防止腦脊液漏

睿康?結(jié)合合成材料的力學(xué)優(yōu)勢和天然材料的貼附能力,在植入初期合成材料發(fā)揮機械力學(xué)優(yōu)勢封閉缺損部位,天然材料形成良好的貼合封閉,防止腦脊液漏。

防止腦脊液漏
參考文獻

[1]  Hoshiba, et al,. Langmuir, 34(13), 4043–4051, 2018.

[2]  Sanders JE, et al,. Biomaterials. Mar;26(7):813-8, 2005.

[3]  Kunxue Deng, Yaya Yang, et al. A Novel Biomimetic Composite Substitute of PLLA/Gelatin Nanofiber Membrane For Dura Repairing. Neurological Research, 2017 July 12.

[4]  Zhidong Shi, Tao Xu, Yuyu Yuan,Kunxue Deng, et al. New Absorbable Synthetic Substitute With Biomimetic Design for Dural Tissue Repair. Artif Organs. 2015 Nov 2. doi: 10.1111/aor.12568. 

[5]  Novel Regenerative Nanofibrous Bio-device for Dural Defect Repair. Congress of Neurological Surgeons Annual Meeting, Washington DC, USA, 2011. 

[6]  In-vitro and clinical study on a novel synthetic absorbable biomimetic dural substitute. European Society for Pediatric Neurosurgery(ESPN) Congress, Rome, Italy, 2014. 

[7]  Electrospum Fibrous Mats with High Porosity as Potential Scaffolds for Skin Tissue Engineering. Biomacromolecules, 2008,9(7):1795-1801. 

[8]  Development of Novel Nanofibrous Dural Substitute for Dural Repair. The 14th World Federation of Neurological Societies Interim Meeting, Pernambuco, Brazil, 2011. 

[9]  Francesco Zenga , et al. Nanofibrous Synthetic Dural Patch for Skull Base Defects: Preliminary Experience for Reconstruction after Extended Endonasal Approaches. Journal of Neurological Surgery Reports 2016;77:e50–e55. 

[10]  Kunxue Deng, Xun Ye, Yaya Yang, Man Liu, et al. Evaluation of efficacy and biocompatibility of a new absorbable synthetic substitute as a dural   onlay graft in a large animal model. Neurological Research 2016.